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Ovarian Reserve Declines with Age

Posted January 03, 2017 in Blog

The anti mullerian hormone is a substance produced by reproductive tissue. Its values indicate the level of ovarian reserve in a woman.

Ovarian reserve (the number and the quality of the eggs) declines with age. Women are born with all the eggs that they will have throughout their lives. When a girl is born she has about 2 million eggs. By the time she reaches puberty that number has declined to 4–5 hundred thousand. Each month from puberty to menopause one egg is released (ovulation) and anywhere between 10 and a 100 will degenerate and be absorbed into the body.

When a women gets evaluated for infertility, one of the things we look for is the ovarian reserve.

Ovarian reserve can be checked by a variety of methods;
1. Ultrasound: to check the number of resting follicles per ovary (6 or more per ovary is associated with good ovarian reserve)
2. AMH level: a hormone measured in the blood. The levels can vary from lab to lab but in general a level more than one is considered good and more than two is considered excellent at any age group. A level of one or less is considered to be consistent with diminished ovarian reserve, or low fertility chances. The numbers do decrease with age so, the younger one is, the higher the number that is expected. If the number is too high (7 or higher) then that may be consistent with polycystic ovarian syndrome (PCOS).
3. FSH and estradiol levels: which are blood tests that are measured during the second or third day of menstrual cycle.
4. Other test have also been used such as inhibin levels (a gonadotropin hormone) and other blood tests.

It is important for patients with fertility issues to undergo a thorough evaluation. The AMH test alone cannot determine a patient’s best course of treatment. The AMH values along with the rest of the evaluation must be interpreted in the context of the whole patient to determine what the best therapy for each individual.

For more information, please contact us. Dr. Peyman Saadat and his team of professionals are here to help. Call us at 310.929.6707 or email us at

Contact Us Today: 310.929.6707

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