Intracytoplasmic Sperm Injection (ICSI)

One of the most important advances in in vitro fertilization IVF treatment is Intracytoplasmic Sperm Injection (ICSI). ICSI is a micromanipulation technique that uses a small needle to inject a single sperm directly into the egg to achieve fertilization during IVF procedure.

How ICSI Contributes to Greater Success

One of the greatest challenges in egg fertilization is the ability of quality sperm to travel up the fallopian tubes in enough quantity and with enough speed, to contact the egg during ovulation. The process of In Vitro Fertilization (IVF) increases the success rate of fertilization by mixing sperm directly with the egg in the laboratory.  The fertilized embryo is then transferred into the uterus where it attempts to implant and grow.

The ICSI Procedure with IVF

In the ICSI process, sperm is collected, washed, and placed in a centrifuge to separate the healthiest cells. The embryologist, using special micromanipulation techniques under microscopic control, selects the most viable sperm and injects a single sperm cell directly into the cytoplasm of each egg that has been retrieved. Each fertilized egg is cultured in the laboratory until it develops into an embryo (3-4 days). At this point, the embryologist and the doctor together select the healthiest and well-developed embryo(s) for transfer. Additional embryos can be frozen for future use.

ICSI is especially useful for treating severe male factor infertility, such as low sperm motility, abnormal sperm morphology, or little or no living sperm in the semen.

ICSI enables doctors to use sperm collected directly from the testicles using techniques such as Testicular Sperm Aspiration (TESA). Fertilization rates using IVF and ICSI in cases of severe male factor infertility are as high or higher than those of couples using IVF with normal sperm. Therefore, individuals with severe male factor infertility that in the past who would have been considered “sterile” can have children using IVF with ICSI at our fertility clinic.

All stages of this fertility treatment take place in our facility. You will see the same familiar faces throughout the entire cycle at our fertility clinic.